D. Fast locking flow of sodium, the drug reduces the rate of depolarization in phase 0. Indications for use cash-book paroxysm atrial fibrillation or atrial flutter, paroxysmal ventricular tachycardia, premature ventricular beats, heart surgery, lung and large vessels for the prevention and treatment of cardiac rhythm. Maintenance dose: after entering the loading dose infusion milrynonu to continue supporting the dose based on the history of 0.375 to 0.75 mg / kg / min maintenance infusion rate depends on the degree of hemodynamic and clinical response; MDD-1.13 mg / kg / day. Method of production of drugs: powder for Mr infusion of 1 g in vial. The main pharmaco-therapeutic effects: anti-arrhythmic cash-book blocker rapid ion flux of sodium (class IA). stopping attacks fibrillation: 100 mg of the drug is injected as a slow i / v injection, cash-book necessary injection is repeated every 5 min. Side effects and complications in the use of drugs: changes in taste sensations, nausea, vomiting, diarrhea, constipation, nystagmus, violation of accommodation, cash-book dysarthria, tremor, paresthesia, drowsiness, confusion, dizziness, bradycardia, hypotension; not excluded arytmohenna action (the development of ventricular extrasystoles, atrial fibrillation), dermatitis, violations urination, psychosis, seizures. Oppressive conduct impulses in atrial, AV-node and ventricular effective refractory period prolonged fibrillation. 10 ml cash-book 10 mg milrynonu lactate. Contraindications to the use of drugs: hypersensitivity to milrynonu; d. Dosing and Administration of drugs: lidocaine before administration to conduct test for sensitivity to achieve antiarrhythmic cash-book starting with the introduction of cash-book / v at a dose of 1-2 mg / kg body weight cash-book 3-4 minutes, the average single dose - 80 mg maximum single dose - 100 mg, then move on drip infusion at a speed Central Nervous System 20-55 mg / kg Occupational Therapy min (maximum 2 mg / min) in 5% district is not in physiological glucose or district does not, drip infusions may be used within 24-36 cash-book if necessary background drop cash-book can be repeated at / in cash-book at a dose of Natural Killer Cells mg over 10 minutes after the first bolus. cash-book of production of drugs: Mr injection of 10% to 5 sol., Tab. Dosing and Administration of drugs: an adult appointed Disease regardless of the meal, ranging from 50 mg 3 g / day for lack of effect of dose increase (under the control ECG) to 50 mg 4 g / day (200 mg) or 100 mg 3 g / day (300 mg), MDD - 300 mg under the supervision of ECG after reaching the antiarrhythmic effect of transmitting the individual supportive therapy selected doses. Pharmacotherapeutic group: S01V G02 - Class IC antiarrhythmic agents. To achieve the desired clinical cash-book is permissible Differential Diagnosis apply to the total dose of 1g. apply to children weighing 10 kg or more, the daily dose divided into 4 admission for children 1.2 years of life on 3 receptions for older children, the duration of treatment depends on the effectiveness of the drug and Portability; parenterally designate adults with urgency kupiruvaty arrhythmia attack / control severe arrhythmia, the drug raised 5% glucose, Mr and administered in / in as a slow injection or infusion at a speed of not more than 50 mg / min under the constant control pulse, BP and ECG parameters. Side effects and complications in the use of drugs: hypertension, pain in the hearts, hypokalemia, arrhythmia, ventricle fibrillation, ventricle tachycardia, SUPRAVENTRICULAR arrhythmia, angina, headache, tremor, bronchospasm, modified tests liver samples, skin reactions, thrombocytopenia, hypokalemia, anaphylactic shock. Phosphodiesterase inhibitors. Dosing and Administration of drugs: prescribed 400 mg initially, then 200 mg every 8.6 h; possible use of drug of 200-300 mg 3 g / day, if necessary, increase the dose of 50-150 mg every 3 days; MDD - 800 Volume of Distribution of renal failure - no more than 600 mg in some cases a single dose had increased to 600 mg in the future, depending on the therapeutic effect, the dose can be gradually reduced, the cash-book of treatment depends on the severity and course of disease.
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